Karen Marie Kelly (Manasco)

Karen Kelly (Manasco) Obituary

November 19, 2023. Karen passed away at age 46 from a dominant rare gene (Kuf’s Disease) Neuronal Ceroid Lipofuscinoses NCL5.  Predeceased by her grandparents, Marjorie and Vernon Kelly; father, Marshall E. Manasco; sister, Susan Jean Reynolds.  She leaves behind her loving, devoted mother, Donna A. Kelly; cousins, Diane (Ronald) Graner and Laura (Alan) Rolnick of Fayetteville, NY; as well as many lifelong friends.  Karen had a smile to brighten anyone’s day throughout her short life.

 Karen graduated from Fairport High School in 3 years.  She was first chosen for the Penn State University Pre-Law Class graduating with undergraduate degrees in Pre-Law (Political Science) and Journalism in 4 years in 1998.  She graduated from Chatham University with a Masters in Education in 2005 with a consortium study at Nazareth College while student teaching at Nazareth Academy.  Karen spent most of her time in the service to others.  She was elected President of her Law School Class at Duquesne University.  While attending graduate school at Chatham University full time, she worked full time as an Intake Counselor in the Child Protective Services in Allegheny County, PA.  She taught high school English, History, and Civics in PA, MD, NY, and NC to many students who would be the first in their families to attend college.  She also was employed by the Wall Street Journal, Leadership Pittsburgh, New York Times, and the Democrat and Chronicle.  She was a published contributor in the Annapolis Capitol, Messenger Posts, and the Democrat and Chronicle.  Karen was a published poet in the International Poetry Society.  She was passionate about our U.S. government and was an active contributor in many Federal, State and Local elections.  While in high school, she received a U.S. Congressional Award for community services from the Honorable Congresswomen Louise Slaughter.  Caring Karen devoted her time to volunteering for the VA Medical Centers in Pittsburgh and Canandaigua, Literacy Program, and Foodlink.

 She recognized the importance of medical research in helping find cures through advancing medical education and research. Karen made an Anatomical Gift Program donation to the University of Rochester Medical School.  

 A special appreciation to the Fairport Baptist Homes Staff who were so kind, caring, and supportive.

 Please consider honoring Karen’s memory with a donation to Dr. Susan Cotman NCL Disorder Research Fund at Massachusetts General Hospital for Genomic Medicine.  Donations may be made online at or checks can be mailed to, with designation to “Cotman Lab/NCL Research”: Massachusetts General Hospital, Development Office, 125 Nashua Street, Suite 540, Boston, MA  02114.
 A graveside service will be held for the family at White Haven Memorial Park at a future date.

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